![]() Therefore, treatment strategies that maintain quality of life without compromising oncologic outcomes have gained attention gradually. Total mesorectal excision (TME), an approved standard surgical treatment for rectal cancer, is associated with perioperative morbidity and impaired quality of life. Keywords: Clinical complete regression Neoadjuvant therapy Rectal neoplasms Watch and wait In this review, oncologic outcomes, ongoing efforts to improve oncologic outcomes, and limitations for clinical practice were evaluated and described. Indeed, advances in local control have not translated into overall survival improvement, and many efforts have been made to improve distant metastasis control and overall survival and improve clinical response to preoperative chemoradiotherapy. However, the appropriate definition and diagnostic method for cCR have not yet been clearly defined. ![]() Adequate patient selection is necessary to achieve favorable oncologic outcomes. ![]() However, a high local regrowth rate is a problem, and proper salvage management is the main concern in the WW approach. Many studies have reported comparable overall survival with WW and radical resection. It is now one of the most interesting issues in rectal cancer treatment. We conducted a systematic review of PubMed for literature published on WW. The number of publications regarding WW for rectal cancer has increased abruptly. Actually, it is not “no surgery” but “deferral of surgery ” therefore, the WW approach or non-operative management is a representative term currently. The WW approach was first introduced by Habr–Gama in patients with cCR after neoadjuvant treatment. Watch and wait (WW) strategies have been suggested for patients with clinical complete regression (cCR).
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |